Suzyme 325mg Tablet

Suzyme 325mg Tablet

Alkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Suzyme should not be used concurrently with antacid.

Indications

Suzyme is employed for the treatment of patients with

• Chronic pancreatitis
• Cystic fibrosis/Mucoviscidosis
• Following partial or complete pancreatectomy
• Total gastrectomy
• Steatorrhea
• Somatostatinoma
• Celiac disease and
• Other conditions associated with pancreatic insufficiency

Composition

Each enteric film-coated tablet contains 325 mg of Pancreatin BP that provides not less than the following enzymatic activity-

• Amylase 7800 units
• Protease 455 units
• Lipase 6500 units

Pharmacology

Pancreatin is a preparation of Pancreatin, an extract from mammalian pancreas containing enzymes with Amylase, Protease and Lipase activity. It is designed to disintegrate in the alkaline medium of the duodenum where it releases the active enzyme components of Pancreatin (Amylase, Protease and Lipase).

Dosage & Administration

2-3 tablets to be swallowed whole with little water immediately after or during meal. Or as directed by the physician

Interaction

Alkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Suzyme should not be used concurrently with antacid.

Contraindications

Pancreatin is contraindicated in patients with known hypersensitivity to the drug.

Side Effects

The most frequent side effects are gastrointestinal including nausea, vomiting and abdominal discomfort. Buccal and perianal soreness may occur, particularly in infants. Hypersensitivity reactions manifested by sneezing, lacrimation or skin rashes have been reported.

Pregnancy & Lactation

Pancreatin should be given to a pregnant woman only if clearly needed. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Pancreatin is administered to a nursing mother.

Precautions & Warnings

Patients known to be allergic to animal protein should be treated with caution.

Overdose Effects

Excessive dosage may produce a laxative effect. Systemic toxicity does not occur. Very high dosage may cause hyperuricaemia and hyperuricosuria

Therapeutic Class

Digestive Enzyme

Storage Conditions

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.