Rex 6mg+200mg+50mg Tablet

Rex 6mg+200 mg+50 mg Tablet

This tablet is administered orally. The adult dose of this combination of antioxidant vitamin tablet is 1 tablet daily or as prescribed by the physician.

Indications

The active ingredients i.e. the antioxidants present in each tablet, namely Vitamin A, Vitamin C & Vitamin E have been linked with reduced risks of cardiovascular diseases in human. All of these three antioxidant vitamins have also been linked with reduced risks of cataract.

Compositio

Each film coated tablet contains-

• Beta carotene (Pro-Vitamin A) USP 6 mg
• Vitamin C (Ascorbic acid) BP 200 mg
• Vitamin E (Alpha Tocopherol) BP 50 mg

Interaction

There is no potentially hazardous drug interactions with retinol (after conversion of beta carotene to it). Both cadmium and copper decreases retinol plasma levels. Among antibiotics, neomycin, and bleomycin reduces the absorption of retinol.

Contraindications

Although human body converts Beta Carotene to Vitamin A only when required, yet excessive doses of Vitamin A should be avoided in pregnancy because of potential teratogenic effects. Patients with hypersensitivity to retinol should not take this preparation, although the possibility of such cases are occasional.

Side Effects

Loose stools may occasionally occur during treatment with beta carotene and the skin may assume a slightly yellow discoloration. The toxic eects of vitamin A (after conversion of beta carotene to it) which are encountered are normally reversible and an irreversible toxic effect is effectively unknown. Chronic overdosage can lead to peeling and redness of the skin, disturbed hair growth, loss of appetite, and sickness.

Pregnancy & Lactation

Vitamin A (retinol): High doses should not be given in pregnancy. High doses of retinol are best avoided by lactating mothers.Vitamin C: The drug is safe in normal doses in pregnant women, but a daily intake of 5 g or more is reported to have caused abortion. The drug may be taken safely during lactation.Vitamin E: The drug may be used in the normally recommended dose, but the safety of high-dose therapy has not been established. There appears to be no contraindication to breast-feeding by mothers taking the normally recommended dose.

Precautions & Warnings

There are some evidences that β carotene may cause harm to heavy smokers and alcoholics. Therefore, caution should be exercised in these cases. Vitamin C should be given with caution to patients with hyperoxaluria. Vitamin E should be used with caution in patients taking anticoagulant drugs, because vitamin E may enhance the anticoagulant activity of these drugs.

Therapeutic Class

Anti-oxidant Multivitamin preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.